If you’re planning an adventure through America’s heartland, this Midwest road trip guide will help you discover scenic drives, hidden gems, and unforgettable experiences along the way. From charming small towns and vast farmlands to crystal-clear lakes and national parks, the Midwest offers some of the most underrated road trip routes in the U.S. Whether you’re a nature lover, history buff, or foodie, these scenic Midwest road trips promise adventure, serenity, and endless photo-worthy stops.
If you need up-to-date weather for the Midwest, visit Weather.com.
Tips for Planning Your Midwest Road Trip
If you’re planning a Colorado budget road trip, don’t miss our guide.
Best Time to Go: From late spring to early fall, you’ll enjoy the most pleasant weather for road trips, nature stops, and picturesque drives.
Pack Smart: Bring layers, comfy hiking shoes, and a camera to capture all the spontaneous stops along the way. You never know when a perfect photo opportunity or scenic spot will pop up!
Plan Stops Ahead: Many small-town attractions close early, so it’s a good idea to check their timings in advance. Planning ahead ensures you don’t miss out on any hidden gems along the way.
Local Eats: Be sure to try local specialties like cheese curds, smoky barbecue, and fresh homemade pies to make your road trip even tastier.
Plan your entire Midwest road trip and explore detailed route maps on MyScenicDrives.
Let’s dive into the 10 best Midwest road trips you can’t miss — perfect for anyone looking to experience America beyond the usual tourist paths.
1. Great River Road – Mississippi River Scenic Drive
If you want the full route and stops, see the Great River Road – Mississippi River Scenic Drive.
Route: If you’re driving from Minnesota to Louisiana, I’d suggest going through Wisconsin, Iowa, Illinois, and Missouri. It’s a scenic route with charming towns and great stops along the way.
If you’re into river views, small-town charm, and cultural history, the Great River Road is a must-see. This scenic Midwest drive follows the Mississippi River, winding past rolling bluffs and historic river towns. Don’t miss Galena, Illinois, with its beautifully preserved 19th-century architecture, or enjoy a craft beer in La Crosse, Wisconsin while taking in the river views.
This route is perfect for those who love slow travel, picturesque scenery, and discovering hidden Midwest gems. In the fall, the foliage along the Great River Road is absolutely stunning — a treat for photographers and outdoor lovers alike.
2. Lake Superior Circle Tour – The Ultimate Great Lakes Adventure
Route: Take a scenic route through Michigan’s Upper Peninsula, then cruise across Wisconsin and Minnesota.
Want a clear route for your Great Lakes trip? See the Lake Superior Circle Tour.
If you’re into waterfalls beaches and nature the Lake Superior Circle Tour is a dream trip You’ll pass Pictured Rocks National Lakeshore the Apostle Islands and Duluth’s North Shore with stops like Copper Harbor Lighthouse Tahquamenon Falls and Split Rock Lighthouse that look like they belong on a postcard. This route is perfect for anyone seeking Great Lakes adventures or Midwest camping road trips.
3. Door County, Wisconsin – The Cape Cod of the Midwest
Route: I suggest taking the trip from Sturgeon Bay to Washington Island for some peaceful island vibes.
If you want a taste of the Cape Cod of the Midwest, check out Door County, Wisconsin, at Destination Door County.
I’d recommend Door County for romantic getaways coastal charm and food lovers — it’s such a hidden gem in the Midwest. Imagine wandering through cherry orchards and quaint harbors or relaxing on peaceful beaches along the shoreline I spent a day at Peninsula State Park hiking the trails and enjoying the sweeping lake views. Don’t miss a classic fish boil dinner at sunset and exploring the local art galleries in town Be sure to take the lighthouse tour every stop offers some of the most scenic views in Wisconsin.
4. The Badlands and Black Hills Loop – South Dakota’s Wild Side
Route: Consider driving from Rapid City to Badlands National Park, then Mount Rushmore, and end at Custer State Park.
If you love rugged landscapes and epic drives, check out the Badlands and Black Hills Loop at Travel South Dakota.
If you’re looking for an amazing South Dakota road trip with national parks and wildlife this route is perfect. I visited Badlands National Park first and the colorful canyons and jagged cliffs completely blew me away Then check out Mount Rushmore and Crazy Horse Memorial and swing by Custer State Park to see bison roaming freely. This drive is great for family-friendly outdoor adventures or anyone who loves Midwest nature photography You’ll also discover hidden scenic pull-offs that make the landscapes even more unforgettable.
5. Route 66 – Illinois to Missouri Segment
Route: For a fun Midwest drive, go from Chicago through Springfield and end in St. Louis.
If you love iconic drives, explore Route 66 from Illinois to Missouri at Historic Route 66.
If you love history or have a soft spot for nostalgia the Illinois to Missouri stretch of Route 66 is made for you. Along the way you’ll discover vintage diners quirky roadside attractions and colorful murals that celebrate the golden age of travel be sure to stop at the Cozy Dog Drive-In in Springfield for a true taste of retro Americana the iconic Chain of Rocks Bridge near St Louis is another highlight you won’t want to miss this drive is perfect for anyone looking to soak in classic Midwest vibes and historic highway adventures.
6. North Shore Scenic Drive – Minnesota’s Coastal Gem
Route: Take a trip from Duluth to Grand Marais, ending at the Canadian border. Plenty of spots to stop and enjoy the view.
Discover hidden gems and stunning views on Minnesota’s North Shore Scenic Drive at Explore Minnesota.
Best for waterfalls, lakeside hikes, and cozy cabins, Minnesota’s North Shore Scenic Drive is hard to beat, stretching along Lake Superior the route offers panoramic lake views, rugged cliffs, and charming small towns. I suggest stopping at Gooseberry Falls, Split Rock Lighthouse, and Lutsen Mountains for an adventure you won’t forget. You might want to wander the nature trails and soak in the serene lake views, and I’d recommend pausing at a quiet cabin getaway to truly relax. From what I’ve seen, this drive is perfect for anyone looking for Midwest lake view road trips, peaceful hikes, and charming photo spots. Imagine the crisp air, sparkling waters, and towering cliffs — it’s easy to see why this part of Minnesota is so captivating.
7. The Great Lakes Road Trip – From Chicago to Mackinac Island
Route: Start in Chicago, make your way to Traverse City, and end at Mackinac Island. The journey is full of lakeside charm and small-town character.
Check out the epic Great Lakes Road Trip from Chicago to Mackinac Island through Pure Michigan.
If you love urban excitement and lakeside relaxation this road trip from Chicago to Mackinac Island has it all starting in Chicago where you can take in the skyline and the buzz of the city then heading north along Lake Michigan’s scenic shoreline. Sleeping Bear Dunes National Lakeshore is a must see with rolling sand dunes and beaches that feel like a world away. Mackinac Island is pure charm — no cars just horse drawn carriages and peaceful streets. You’ll find this route perfect for mixing city adventures historic landmarks and serene lake views all in one trip.
8. Flint Hills Scenic Byway – Kansas’ Rolling Prairie Beauty
Route: Travel from Strong City to Cassoday and take in the charming small-town views along the route.
If you’re planning a scenic adventure, visit this Flint Hills Scenic Byway TravelKS.
For anyone who loves peaceful drives scenic photography and open landscapes the Flint Hills Scenic Byway is a must. I drove it recently and was amazed by the endless prairies and towering limestone bluffs that stretch as far as the eye can see.You’ll want to stop often to enjoy the quiet scenery and capture some incredible photos, this route is perfect for anyone looking for relaxing Midwest road trips or a peaceful escape into nature. From what I’ve experienced it’s one of the most charming and untouched drives in Kansas.
Stop at the Tallgrass Prairie National Preserve, where you can hike, photograph wildlife, or simply enjoy the stillness.
9. The Great River Bluffs – Iowa’s Driftless Area
Route: Drive from Decorah through McGregor and end in Lansing. Along the way, you’ll find charming small towns and scenic rivers.
For stunning scenery at the Great River Bluffs, visit Travel Iowa.
This Iowa road trip is perfect for river views, hiking, and small-town charm, with the Driftless Area featuring rugged beauty, dramatic cliffs and rolling hills that glaciers never touched, Effigy Mounds National Monument showcasing ancient earthworks against stunning natural scenery and nearby local wineries offering regional flavors in a peaceful setting. Riverside bed-and-breakfasts make it easy to relax, soak in the quiet charm of the area and enjoy history, scenic landscapes, and small-town experiences for a memorable and rejuvenating journey for anyone who loves nature and culture.
10. The Ozarks Scenic Drive – Missouri’s Natural Playground
Route: From Springfield to Branson, through Eminence, and finally to the Lake of the Ozarks. It’s a scenic route perfect for a relaxing road trip.
Discover the beauty of the Ozarks Scenic Drive in Missouri Travel.
The Ozarks region is full of hidden caves, sparkling lakes, and scenic state parks, making for an unforgettable drive. Explore Ha Ha Tonka State Park, where trails, castles and natural springs offer amazing photo opportunities and enjoy live music in Branson, a lively town full of entertainment and local charm, don’t miss a boat ride on Lake of the Ozarks to soak in the beautiful waters and surrounding landscapes, a route many find perfect for family-friendly Midwest road trips that combine adventure, relaxation, and unique experiences.
It’s among the best Midwest family road trips, blending adventure, nature, and relaxation.
FAQs About Midwest Road Trips
Q1. What’s the most scenic road trip in the Midwest?
I’d recommend the Lake Superior Circle Tour or Great River Road for stunning views.
Q2. How many days do I need for a Midwest road trip?
You might want to plan 5–10 days for the best experience.
Q3. Are Midwest road trips good for families?
Definitely! You’ll enjoy family-friendly routes like the Ozarks and Black Hills.
Q4. When’s the best time to see fall colors in the Midwest?
Fun fact — early to mid-October offers the most vibrant colors.
Q5. Are Midwest road trips expensive?
Not at all! You’ll find them affordable and easy on the wallet.
My Experience
During my Midwest road trip, I discovered a few tips that made the journey smoother and more enjoyable. I suggest planning your stops ahead, especially in small towns, since attractions can close early. I also recommend packing layers and comfy shoes because the weather can change quickly and some trails can be tricky. Lastly, I suggest trying local specialties at every stop — whether it’s cheese curds in Wisconsin or a fish boil in Door County — it really adds flavor to your adventure!
So fuel up, roll down your windows, and set out on an unforgettable journey across America’s heartland — where the roads are open, the skies are wide, and the memories last forever.